Article
Mitochondrial somatic mutations and the lack of viral genomic variation in recurrent respiratory papillomatosis.
Scientific reports - 12 Nov 2019
Hao Yuhan, Ruiz Ryan, Yang Liying, Neto Antonio Galvao, Amin Milan R, Kelly Dervla, Achlatis Stratos, Roof Scott, Bing Renjie, Kannan Kasthuri, Brown Stuart M, Pei Zhiheng, Branski Ryan C
Abstract excerpt
Recurrent Respiratory Papillomatosis (RRP) is a rare disease of the aerodigestive tract caused by the Human Papilloma Virus (HPV) that manifests as profoundly altered phonatory and upper respiratory anatomy. Current therapies are primarily symptomatic; enhanced insight regarding disease-specific biology of RRP is critical to improved therapeutics for this challenging population. Multiplex PCR was performed on...
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