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Article

Secondary Structural Model of Human MALAT1 Reveals Multiple Structure-Function Relationships.

International journal of molecular sciences - 9 Nov 2019

McCown Phillip J, Wang Matthew C, Jaeger Luc, Brown Jessica A

Abstract excerpt

Human metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is an abundant nuclear-localized long noncoding RNA (lncRNA) that has significant roles in cancer. While the interacting partners and evolutionary sequence conservation of MALAT1 have been examined, much of the structure of MALAT1 is unknown. Here, we propose a hypothetical secondary structural model for 8425 nucleotides of human MALAT1 using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31717552
DOI: 10.3390/ijms20225610
PMCID: PMC6888369

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