Article
The long noncoding RNA Malat1: Its physiological and pathophysiological functions.
RNA biology - 2 Dec 2017
Zhang Xuejing, Hamblin Milton H, Yin Ke-Jie
Abstract excerpt
Recent studies suggest that in humans, DNA sequences responsible for protein coding regions comprise only 2% of the total genome. The rest of the transcripts result in RNA transcripts without protein-coding ability, including long noncoding RNAs (lncRNAs). Different from most members in the lncRNA family, the metastasis-associated lung adenocarcinoma transcript 1 (Malat1) is abundantly expressed and...
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