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MRI Scoring Systems for Predicting Isocitrate Dehydrogenase Mutation and Chromosome 1p/19q Codeletion in Adult-type Diffuse Glioma Lacking Contrast Enhancement.

Radiology - 1 May 2024

Kang Koung Mi, Song Jiyoung, Choi Yunhee, Park Chanrim, Park Ji Eun, Kim Ho Sung, Park Sung-Hye, Park Chul-Kee, Choi Seung Hong

Abstract excerpt

Background According to 2021 World Health Organization criteria, adult-type diffuse gliomas include glioblastoma, isocitrate dehydrogenase (IDH)-wildtype; oligodendroglioma, IDH-mutant and 1p/19q-codeleted; and astrocytoma, IDH-mutant, even when contrast enhancement is lacking. Purpose To develop and validate simple scoring systems for predicting IDH and subsequent 1p/19q codeletion status in gliomas without...

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PMID: 38713025
DOI: 10.1148/radiol.233120

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