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Antivirulence and avirulence genes in human pathogenic fungi

1 Jan 2019

Abstract excerpt

Opportunistic commensal and environmental fungi can cause superficial to systemic diseases in humans. But how did these pathogens adapt to infect us and how does host-pathogen co-evolution shape their virulence potential? During evolution toward pathogenicity, not only do microorganisms gain virulence genes, but they also tend to lose non-adaptive genes in the host niche. Additionally, virulence factors can...

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PMID: 31711357
DOI: 10.1080/21505594.2019.1688753

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