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Article

Osteosarcoma‐initiating cells show high aerobic glycolysis and attenuation of oxidative phosphorylation mediated by LIN28B

9 Nov 2019

Abstract excerpt

Abstract Osteosarcoma (OS) is a highly malignant bone tumor and the prognosis for non‐responders to chemotherapy remains poor. Previous studies have shown that human sarcomas contain sarcoma‐initiating cells (SIC), which have the characteristics of high tumorigenesis and resistance to chemotherapy. In the present study, we characterized SIC of a novel OS cell line, screened for SIC‐related genes, and tried to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31705593
DOI: 10.1111/cas.14229

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