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Exploring the relationship between metabolism and immune microenvironment in osteosarcoma based on metabolic pathways

11 Jan 2024

Abstract excerpt

BACKGROUND: Metabolic remodeling and changes in tumor immune microenvironment (TIME) in osteosarcoma are important factors affecting prognosis and treatment. However, the relationship between metabolism and TIME needs to be further explored. METHODS: RNA-Seq data and clinical information of 84 patients with osteosarcoma from the TARGET database and an independent cohort from the GEO database were included in this...

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PMID: 38212768
DOI: 10.1186/s12929-024-00999-7

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