Article
The Molecular Basis of Congenital Hypopituitarism and Related Disorders.
The Journal of clinical endocrinology and metabolism - 1 Jun 2020
Gregory Louise Cheryl, Dattani Mehul Tulsidas
Abstract excerpt
CONTEXT: Congenital hypopituitarism (CH) is characterized by the presence of deficiencies in one or more of the 6 anterior pituitary (AP) hormones secreted from the 5 different specialized cell types of the AP. During human embryogenesis, hypothalamo-pituitary (HP) development is controlled by a complex spatio-temporal genetic cascade of transcription factors and signaling molecules within the hypothalamus and...
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