Article
Co-mutation landscape and prognostic impact of genomic complexity in EGFR-mutant non-small cell lung cancer.
BMC cancer - 11 Aug 2026
Yang Xiangdi, Huang Guojian, Liu Kejun, Wang Dongxia, Wang June, Huang Meixia, Huang Linxuan
Abstract excerpt
METHODS: Clinical and genomic data of patients with EGFR-mutant NSCLC were collected from publicly available cBioPortal cohorts. Cohort composition, stage availability, recurrent co-mutations, and study-origin heterogeneity were evaluated. Patients harboring EGFR Del19 or L858R mutations and available survival information were included for survival analyses. Genomic landscapes were analyzed using a standardized...
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- Humans
- Carcinoma, Non-Small-Cell Lung
- Prognosis
- ErbB Receptors
- Mutation
- Lung Neoplasms
- Female
- Male
- Middle Aged
- Aged