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Article

Mutation and immune profiling of metaplastic breast cancer: Correlation with survival.

PloS one - 1 Jan 2019

Afkhami Michelle, Schmolze Daniel, Yost Susan E, Frankel Paul H, Dagis Andrew, Amanam Idoroenyi U, Telatar Milhan, Nguyen Kim, Yu Kim Wai, Luu Thehang, Pillai Raju, Aoun Patricia A, Mortimer Joanne, Yuan Yuan

Abstract excerpt

The goal of this study is to characterize the genomic and immune profiles of metaplastic breast cancer (MpBC) and identify the association with survival through an analysis of archived tumor tissue. A next-generation sequencing-based mutational assay (Onco-48) was performed for 21 MpBC patients. Clinicopathologic characteristics were captured, including relapse free survival (RFS) and overall survival (OS)....

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Identifiers

PMID: 31693690
DOI: 10.1371/journal.pone.0224726
PMCID: PMC6834262

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