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Article

Identification of a novel somatic mutation of POU6F2 by whole-genome sequencing in prolactinoma.

Molecular genetics & genomic medicine - 1 Dec 2019

Miao Yazhou, Li Chuzhong, Guo Jing, Wang Hongyun, Gong Lei, Xie Weiyan, Zhang Yazhuo

Abstract excerpt

BACKGROUND: Pituitary adenomas (PAs) are one of the most common intracranial tumors; approximately half of PAs are prolactin (PRL)-secreting PAs (prolactinomas). The genetic alterations prevalent in prolactinomas are unknown. METHODS: Here, we present a patient with an extremely aggressive and giant prolactinoma accompanied by serious destruction of the surrounding bone mass. This patient exhibited resistance to...

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Identifiers

PMID: 31692290
DOI: 10.1002/mgg3.1022
PMCID: PMC6900357

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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