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Article

Genetic association of ARHGAP21 gene variant with mandibular prognathism.

Journal of dental research - 1 Apr 2015

Perillo L, Monsurrò A, Bonci E, Torella A, Mutarelli M, Nigro V

Abstract excerpt

Mandibular prognathism (MP) is a recognizable phenotype associated with dentoskeletal class III malocclusion. MP is a complex genetic trait, although familial recurrence also suggests the contribution of single inherited variations. To date, the genetic causes of MP have been investigated using linkage analysis or association studies in pooled families. Here for the first time, next-generation sequencing was used...

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Source

Identifiers

PMID: 25691070
DOI: 10.1177/0022034515572190

Genes

ARHGAP21
ANXA2
BMP3
FLNB
HOXA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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