Article
The hTERT-VNTR2-2nd alleles are involved in genomic stability in gastrointestinal cancer.
Genes & genomics - 1 Dec 2019
Kwon Jeong-Ah, Jeong Mi-So, Yoon Se-Lyun, Mun Jeong-Yeon, Kim Min-Hye, Yang Gi-Eun, Park Seong-Hwan, Chung Jin-Woong, Choi Yung Hyun, Cha Hee-Jae, Leem Sun-Hee
Abstract excerpt
BACKGROUND: hTERT contains a high density of minisatellites, of which rare alleles of hTERT-VNTR2-2nd have been reported to be associated with prostate cancer. This shows an association between VNTR and cancer, but this repeat sequence is likely to be associated with genomic instability. Therefore, we investigated the effects of hTERT-VNTR2-2nd on gastrointestinal cancer and the relationship between repeated...
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