Article
ALK-rearranged renal cell carcinomas in Polish population.
Pathology, research and practice - 1 Dec 2019
Gorczynski Adam, Czapiewski Piotr, Korwat Aleksandra, Budynko Lukasz, Prelowska Monika, Okon Krzysztof, Biernat Wojciech
Abstract excerpt
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase, the activation of which is considered an important event in the pathogenesis of several neoplasms and a predictive factor for the targeted therapy with ALK inhibitors. Thus far, ALK rearrangements have been identified in 22 renal cell carcinomas in both pediatric and adult patients. We evaluated the incidence of ALK rearrangement-associated RCC in...
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