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Article

Fine-Mapping Complex Inversion Breakpoints and Investigating Somatic Pairing in the Anopheles gambiae Species Complex Using Proximity-Ligation Sequencing

30 Oct 2019

Abstract excerpt

Abstract In this work, Corbett-Detig et al. use proximity-ligation sequencing (Hi-C) of several Anopheles gambiae and A. coluzzii inversionbearing individuals to detect and map inversion breakpoints. They show that inversion breakpoints can be mapped precisely... Chromosomal inversions are fundamental drivers of genome evolution. In the main Afrotropical malaria vector species, belonging to the Anopheles gambiae...

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PMID: 31666292
DOI: 10.1534/genetics.119.302385

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