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Article

Zika Virus NS2A-Mediated Virion Assembly.

mBio - 29 Oct 2019

Zhang Xianwen, Xie Xuping, Xia Hongjie, Zou Jing, Huang Linfen, Popov Vsevolod L, Chen Xinwen, Shi Pei-Yong

Abstract excerpt

The flavivirus virion consists of an envelope outer layer, formed by envelope (E) and membrane (M) proteins on a lipid bilayer, and an internal core, formed by capsid (C) protein and genomic RNA. The molecular mechanism of flavivirus assembly is not well understood. Here, we show that Zika virus (ZIKV) NS2A protein recruits genomic RNA, the structural protein prM/E complex, and the NS2B/NS3 protease complex to...

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Identifiers

PMID: 31662457
DOI: 10.1128/mBio.02375-19
PMCID: PMC6819661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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