Article
Characterization and pathogenicity of Vero cell-attenuated porcine epidemic diarrhea virus CT strain.
Virology journal - 28 Oct 2019
Wu Yu, Li Wei, Zhou Qingfeng, Li Qunhui, Xu Zhichao, Shen Hanqin, Chen Feng
Abstract excerpt
BACKGROUND: Porcine epidemic diarrhea virus (PEDV) has caused enormous economic losses to the global pig industry. Currently available PEDV vaccine strains have limited protective effects against PEDV variant strains. METHODS: In this study, the highly virulent epidemic virus strain CT was serially passaged in Vero cells for up to 120 generations (P120). Characterization of the different passages revealed that...
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