Article
A Virulent PEDV Strain FJzz1 with Genomic Mutations and Deletions at the High Passage Level Was Attenuated in Piglets via Serial Passage In Vitro.
Virologica Sinica - 1 Oct 2021
Chen Pengfei, Zhao Xiongwei, Zhou Shuting, Zhou Tianxing, Tan Xiangmei, Wu Xia, Tong Wu, Gao Fei, Yu Lingxue, Jiang Yifeng, Yu Hai, Yang Zhibiao, Tong Guangzhi, Zhou Yanjun
Abstract excerpt
Highly virulent porcine epidemic diarrhea virus (PEDV) strains re-emerged and circulated in China at the end of 2010, causing significant economic losses in the pork industry worldwide. To understand the genetic dynamics of PEDV during its passage in vitro, the PEDV G2 strain FJzz1 was serially propagated in Vero cells for up to 200 passages. The susceptibility and adaptability of the FJzz1 strain increased...
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