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Article

Infrared biomarkers of impaired cystic fibrosis transmembrane regulator protein biogenesis.

Journal of biophotonics - 1 Jan 2020

Bellisola Giuseppe, Caldrer Sara, Cestelli-Guidi Mariangela, Cinque Gianfelice

Abstract excerpt

The mid-infrared (IR) spectra of human cystic fibrosis (CF) cells acquired by Fourier transform infrared microspectroscopy were compared with those of non-CF cells. Within the 1700 to 1480 cm-1 spectral domain of amides, unsupervised explorative principal component analysis identified a few variables reflecting quantitative and qualitative vibrations arising from protein secondary structures and amino acid side...

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Identifiers

PMID: 31654605
DOI: 10.1002/jbio.201900174

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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