Article
Smooth muscle differentiation shapes domain branches during mouse lung development.
Development (Cambridge, England) - 25 Nov 2019
Goodwin Katharine, Mao Sheng, Guyomar Tristan, Miller Erin, Radisky Derek C, Košmrlj Andrej, Nelson Celeste M
Abstract excerpt
During branching morphogenesis, a simple cluster of cells proliferates and branches to generate an arborized network that facilitates fluid flow. The overall architecture of the mouse lung is established by domain branching, wherein new branches form laterally off the side of an existing branch. The airway epithelium develops concomitantly with a layer of smooth muscle that is derived from the embryonic...
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