miR‐223‐3p promotes autoreactive T h 17 cell responses in experimental autoimmune uveitis (EAU) by inhibiting transcription factor FOXO3 expression

Abstract excerpt

Pathogenic T helper (T h )17 cells are key mediators of autoimmune diseases such as uveitis and its animal model, experimental autoimmune uveitis (EAU). However, the contribution of microRNAs (miRs) to the intrinsic control of pathogenic T h 17 cells in EAU remains largely unknown. Here, we have reported that miR‐223‐3p was significantly up‐regulated in interphotoreceptor retinoid‐binding protein‐specific T h 17...

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