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Article

Molecular characterization of hepatitis C virus in liver disease patients in Botswana: a retrospective cross-sectional study.

BMC infectious diseases - 22 Oct 2019

Bhebhe Lynnette, Anderson Motswedi, Souda Sajini, Choga Wonderful T, Zumbika Edward, Shaver Zachary M, Mbangiwa Tshepiso, Phinius Bonolo B, Banda Chabeni C, Melamu Pinkie, Musonda Rosemary M, Essex Max, Blackard Jason T, Moyo Sikhulile, Gaseitsiwe Simani

Abstract excerpt

BACKGROUND: Hepatitis C virus (HCV) infection is a major cause of chronic liver disease globally. Direct acting antivirals (DAAs) have proven effective in curing HCV. However, the current standard of care (SOC) in Botswana remains PEGylated interferon-α (IFN-α) with ribavirin. Several mutations have been reported to confer resistance to interferon-based treatments. Therefore, there is a need to determine HCV...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31640596
DOI: 10.1186/s12879-019-4514-1
PMCID: PMC6805647

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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