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In-utero stress and mode of conception: impact on regulation of imprinted genes, fetal development and future health

13 Jul 2019

Abstract excerpt

BACKGROUND: Genomic imprinting is an epigenetic gene regulatory mechanism; disruption of this process during early embryonic development can have major consequences on both fetal and placental development. The periconceptional period and intrauterine life are crucial for determining long-term susceptibility to diseases. Treatments and procedures in assisted reproductive technologies (ART) and adverse in-utero...

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Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting
Share to Gestational Trophoblastic Disease Studies

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PMID: 31633761
DOI: 10.1093/humupd/dmz025

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