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Respiratory syncytial virus nonstructural proteins 1 and 2: Exceptional disrupters of innate immune responses

17 Oct 2019

Abstract excerpt

Human respiratory syncytial virus (RSV) is the most important cause of acute lower respiratory tract disease in infants worldwide. As a first line of defense against respiratory infections, innate immune responses, including the production of type I and III interferons (IFNs), play an important role. Upon infection with RSV, multiple pattern recognition receptors (PRRs) can recognize RSV-derived...

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PMID: 31622448
DOI: 10.1371/journal.ppat.1007984

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