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Methylation estimates the risk of precancer in HPV-infected women with discrepant results between cytology and HPV16/18 genotyping

12 Oct 2019

Abstract excerpt

BACKGROUND: Vigilant management of women with high-risk human papillomavirus (hrHPV) is necessary in cancer screening programs. To this end, we evaluated the performance of S5 (targeting DNA methylation in HPV16, HPV18, HPV31, HPV33, and human gene EPB41L3) to predict cervical intraepithelial neoplasia grade 2 or higher (CIN2+) in a sample of hrHPV-infected women referred to colposcopy in the FRIDA Study, a large...

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Share to Cervical Cancer and HPV Research
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31606044
DOI: 10.1186/s13148-019-0743-9

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