Article
Why Glycosylation Matters in Building a Better Flu Vaccine
11 Oct 2019
Abstract excerpt
-glycosylation consensus sequences (sequons, NXT/NXS, rarely NXC) on the HA globular domain occurs among the more prevalent mutations as an IAV strain undergoes antigenic drift. The appearance of new glycosylation shields underlying amino acid residues from antibody contact, tunes receptor specificity, and balances receptor avidity with virion escape, all of which help maintain viral propagation through seasonal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
