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Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer’s disease

17 Sept 2019

Abstract excerpt

Studies of rodent models of Alzheimer's disease (AD) and of human tissues suggest that the retinal changes that occur in AD, including the accumulation of amyloid beta (Aβ), may serve as surrogate markers of brain Aβ levels. As Aβ has a wavelength-dependent effect on light scatter, we investigate the potential for in vivo retinal hyperspectral imaging to serve as a biomarker of brain Aβ. Significant differences...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31530809
DOI: 10.1038/s41467-019-12242-1

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