Article
S1PR3 deficiency alleviates radiation‐induced pulmonary fibrosis through the regulation of epithelial–mesenchymal transition by targeting miR‐495‐3p
5 Sept 2019
Abstract excerpt
Radiation-induced pulmonary fibrosis (RIPF) is a life-threatening complication of thoracic radiotherapy, which contributes to continued deterioration in pulmonary function. Sphingosine-1 phosphate receptor 3 (S1PR3) has been identified as a crucial molecule in fibrosis. Accumulating evidence indicated that the inhibition of the S1PRs ameliorates fibrogenesis. Thus, this study aims to explore whether S1PR3...
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