Article
Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood
2 Sept 2019
Abstract excerpt
More than 7 million individuals have been conceived by Assisted Reproductive Technologies (ART) and there is clear evidence that ART is associated with a range of adverse early life outcomes, including rare imprinting disorders. The periconception period and early embryogenesis are associated with widespread epigenetic remodeling, which can be influenced by ART, with effects on the developmental trajectory in...