Article
Epigenetics and assisted reproductive technologies.
Acta obstetricia et gynecologica Scandinavica - 1 Jan 2016
Pinborg Anja, Loft Anne, Romundstad Liv B, Wennerholm Ulla-Britt, Söderström-Anttila Viveca, Bergh Christina, Aittomäki Kristiina
Abstract excerpt
Epigenetic modification controls gene activity without changes in the DNA sequence. The genome undergoes several phases of epigenetic programming during gametogenesis and early embryo development, coinciding with assisted reproductive technologies (ART) treatments. Imprinting disorders have been associated with ART techniques, but disentangling the influence of the ART procedures per se from the effect of the...
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