Article
A cell-free DNA metagenomic sequencing assay that integrates the host injury response to infection
26 Aug 2019
Abstract excerpt
High-throughput metagenomic sequencing offers an unbiased approach to identify pathogens in clinical samples. Conventional metagenomic sequencing, however, does not integrate information about the host, which is often critical to distinguish infection from infectious disease, and to assess the severity of disease. Here, we explore the utility of high-throughput sequencing of cell-free DNA (cfDNA) after bisulfite...
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