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Urinary cell-free DNA is a versatile analyte for monitoring infections of the urinary tract

14 Jun 2018

Abstract excerpt

Urinary tract infections are one of the most common infections in humans. Here we tested the utility of urinary cell-free DNA (cfDNA) to comprehensively monitor host and pathogen dynamics in bacterial and viral urinary tract infections. We isolated cfDNA from 141 urine samples from a cohort of 82 kidney transplant recipients and performed next-generation sequencing. We found that urinary cfDNA is highly...

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PMID: 29925834
DOI: 10.1038/s41467-018-04745-0

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