Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolutionary Differences in the Vegf/Vegfr Code Reveal Organotypic Roles for the Endothelial Cell Receptor Kdr in Developmental Lymphangiogenesis

1 Aug 2019

Abstract excerpt

Lymphatic vascular development establishes embryonic and adult tissue fluid balance and is integral in disease. In diverse vertebrate organs, lymphatic vessels display organotypic function and develop in an organ-specific manner. In all settings, developmental lymphangiogenesis is considered driven by vascular endothelial growth factor (VEGF) receptor-3 (VEGFR3), whereas a role for VEGFR2 remains to be fully...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenesis and VEGF in Cancer
Share to Congenital heart defects research
Share to Lymphatic System and Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31433980
DOI: 10.1016/j.celrep.2019.07.055

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolutionary Differences in the Vegf/Vegfr Code Reveal Organotypic Roles for the Endothelial Cell Receptor Kdr in Developmental LymphangiogenesisPMID 31433980Read ↗

Vegfd modulates both angiogenesis and lymphangiogenesis during zebrafish embryonic developmentSemantic proximity Read ↗

VEGFR signaling during lymphatic vascular development: From progenitor cells to functional vesselsSemantic proximity Read ↗

The physiological and pathological functions of VEGFR3 in cardiac and lymphatic development and related diseases.Semantic proximity Read ↗

Vegfd can compensate for loss of Vegfc in zebrafish facial lymphatic sproutingSemantic proximity Read ↗

Molecular control of lymphangiogenesisSemantic proximity Read ↗

Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesisSemantic proximity Read ↗

<i>lyve1</i> expression reveals novel lymphatic vessels and new mechanisms for lymphatic vessel development in zebrafishSemantic proximity Read ↗

Role of VEGF-D and VEGFR-3 in developmental lymphangiogenesis, a chemicogenetic study in Xenopus tadpolesSemantic proximity Read ↗

Vegfc acts through ERK to induce sprouting and differentiation of trunk lymphatic progenitors.Semantic proximity Read ↗

Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries.Semantic proximity Read ↗

VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesisSemantic proximity Read ↗

Development of the Zebrafish Lymphatic System Requires Vegfc SignalingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.