MC4R variants rs12970134 and rs17782313 are associated with obese polycystic ovary syndrome patients in the Western region of Saudi Arabia.

doi:10.1186/s12881-019-0876-x

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Article

MC4R variants rs12970134 and rs17782313 are associated with obese polycystic ovary syndrome patients in the Western region of Saudi Arabia.

BMC medical genetics - 20 Aug 2019

Batarfi Asma A, Filimban Najlaa, Bajouh Osama S, Dallol Ashraf, Chaudhary Adeel G, Bakhashab Sherin

Abstract excerpt

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine disorder causing infertility in reproductive-age women. The cause of PCOS is not fully understood but it is thought to be influenced by environmental and genetic factors. Obesity is greatly related to PCOS and its reduction is one of the major aims in treating PCOS. Melanocortin 4 receptor (MC4R) gene polymorphisms were detected to be associated...

Topics

Adolescent
Adult
Alleles
Body Mass Index
Case-Control Studies
Female
Gene Frequency
Genetic Predisposition to Disease
Genetic Variation
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Logistic Models

Obesity

Polycystic Ovary Syndrome

Polymorphism, Single Nucleotide

Receptor, Melanocortin, Type 4

Saudi Arabia

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 31429705
DOI: 10.1186/s12881-019-0876-x
PMCID: PMC6701028

Genes

MC4R

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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MC4R variants rs12970134 and rs17782313 are associated with obese polycystic ovary syndrome patients in the Western region of Saudi Arabia.PMID 31429705Read ↗

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