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Article

Proteomic Analysis of Dpy19l2‐Deficient Human Globozoospermia Reveals Multiple Molecular Defects

19 Aug 2019

Abstract excerpt

PURPOSE: To investigate the differences in protein expression between Dpy19l2-deficient human globozoospermia and normozoospermia. EXPERIMENTAL DESIGN: Human sperm samples from three globozoospermic donors with Dpy19l2 deletion and three normal controls are subjected to TMT quantitative technology. SPESP1, HIST1H4A, and LYZL1 are randomly selected for western blotting analysis. GO annotations are performed using...

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PMID: 31424156
DOI: 10.1002/prca.201900007

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