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Novel DPY19L2 variants in globozoospermic patients and the overcoming this male infertility

16 Oct 2018

Abstract excerpt

Globozoospermia has been reported to be a rare but severe causation of male infertility, which results from the failure of acrosome biogenesis and sperm head shaping. Variants of dpy-19-like 2 (DPY19L2) are highly related to globozoospermia, but related investigations have been mainly performed in patients from Western countries. Here, we performed a screening of DPY19L2 variants in a cohort of Chinese...

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Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Reproductive Biology and Fertility
Sperm and Testicular Function

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30333325
DOI: 10.4103/aja.aja_79_18

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