Article
DPY19L2 gene mutations are a major cause of globozoospermia: identification of three novel point mutations.
Molecular human reproduction - 1 Jun 2013
Zhu Fuxi, Gong Fei, Lin Ge, Lu Guangxiu
Abstract excerpt
Globozoospermia, characterized by round-headed spermatozoa without acrosomes, is a rare and severe teratozoospermia causing primary male infertility. Homozygous DPY19L2 deletions have been identified as the main cause of globozoospermia, blocking sperm head elongation and acrosome formation. Several previous studies showed a very different prevalence of DPY19L2 gene deletions among globozoospermic patients in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.