Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of the arecoline/YAP1/BMP4 pathway in promoting endothelial‐mesenchymal transition in oral submucous fibrosis

9 Aug 2019

Abstract excerpt

BACKGROUND: Oral submucous fibrosis (OSF) is a potentially malignant lesion characterized by epithelial-mesenchymal transition (EMT). Bone morphogenetic protein 4 (BMP4) promotes EMT in fibrotic diseases, but the underlying mechanisms and its potential role in OSF are unclear. This study investigates whether BMP4 plays a role in the pathogenesis of OSF and explores the underlying mechanisms. METHODS: The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genital Health and Disease
Share to Hippo pathway signaling and YAP/TAZ
Share to Oral Health Pathology and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31397922
DOI: 10.1111/jop.12945

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of the arecoline/YAP1/BMP4 pathway in promoting endothelial‐mesenchymal transition in oral submucous fibrosisPMID 31397922Read ↗

miR-203 inhibits arecoline-induced epithelial-mesenchymal transition by regulating secreted frizzled-related protein 4 and transmembrane-4 L six family member 1 in oral submucous fibrosisSemantic proximity Read ↗

Exosomal miR-17-5p derived from epithelial cells is involved in aberrant epithelium-fibroblast crosstalk and induces the development of oral submucosal fibrosisSemantic proximity Read ↗

Arecoline suppresses epithelial cell viability by upregulating tropomyosin-1 through the transforming growth factor-β/Smad pathwaySemantic proximity Read ↗

Arecoline Is Associated With Inhibition of Cuproptosis and Proliferation of Cancer-Associated Fibroblasts in Oral Squamous Cell Carcinoma: A Potential Mechanism for Tumor MetastasisSemantic proximity Read ↗

Exosomal miR-17-5p derived from epithelial cells is involved in aberrant epithelium-fibroblast cross-talk and induces the development of oral submucosal fibrosisSemantic proximity Read ↗

Elevation of Twist expression by arecoline contributes to the pathogenesis of oral submucous fibrosisSemantic proximity Read ↗

Aberrant SSEA-4 upregulation mediates myofibroblast activity to promote pre-cancerous oral submucous fibrosisSemantic proximity Read ↗

Positive Feedback Loop of SNAIL-IL-6 Mediates Myofibroblastic Differentiation Activity in Precancerous Oral Submucous FibrosisSemantic proximity Read ↗

Discovery of Novel Biomarkers in Oral Submucous Fibrosis by Microarray AnalysisSemantic proximity Read ↗

Inhibition of HIF1A-AS1 impedes the arecoline-induced migration activity of human oral mucosal fibroblastsSemantic proximity Read ↗

Role of areca nut induced JNK/ATF2/Jun axis in the activation of TGF-β pathway in precancerous Oral Submucous FibrosisSemantic proximity Read ↗

Immunopathogenesis of oral submucous fibrosis by chewing the areca nutSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.