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Article

Exercise restores dysregulated gene expression in a mouse model of arrhythmogenic cardiomyopathy

24 Jul 2019

Abstract excerpt

AIMS: Arrhythmogenic cardiomyopathy (ACM) is a myocardial disease caused mainly by mutations in genes encoding desmosome proteins ACM patients present with ventricular arrhythmias, cardiac dysfunction, sudden cardiac death, and a subset with fibro-fatty infiltration of the right ventricle predominantly. Endurance exercise is thought to exacerbate cardiac dysfunction and arrhythmias in ACM. The objective was to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31350552
DOI: 10.1093/cvr/cvz199

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