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Allele-specific real-time PCR testing for minor macrolide-resistant Mycoplasma Pneumoniae

12 Jul 2019

Abstract excerpt

BACKGROUND: The point mutations in 23S rRNA gene of Mycoplasma pneumoniae (M. pneumoniae) can lead to high-level resistance to macrolides. This study aimed to evaluate allele-specific real-time PCR (ASPCR) to detect the resistance-related mutations located at positions A2063G and A2064G of 23S rRNA gene. METHODS: We detected 178 pharyngeal swab specimens and calculated the proportions of resistant and sensitive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31299916
DOI: 10.1186/s12879-019-4228-4

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