Article
A single tube modified allele-specific-PCR for rapid detection of erythromycin-resistant Mycoplasma pneumoniae in Beijing.
Chinese medical journal - 1 Aug 2012
Li Shao-Li, Sun Hong-Mei, Zhao Han-Qing, Cao Ling, Yuan Yi, Feng Yan-Ling, Xue Guan-Hua
Abstract excerpt
BACKGROUND: Mycoplasma pneumoniae (M. pneumoniae) is one of the common pathogens causing atypical pneumonia. In recent years, resistance to macrolides has become more common, especially in China. Previous studies have confirmed that the mutation at position 2063 in domain V of the 23S rRNA is the most prevalent, followed by the mutation at position 2064. Reported molecular detection methods for the identification...
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