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Role of Autophagy in Renal Cancer

1 Jan 2019

Abstract excerpt

Autophagy is a highly conserved catabolic process with critical functions in maintenance of cellular homeostasis under normal growth conditions and in preservation of cell viability under stress. The role of autophagy in cancer is dual-sided. Autophagy-deficient cells are often more tumorigenic than their wild type counterparts in association with DNA damage accumulation, oxidative stress. At the same time,...

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PMID: 31258756
DOI: 10.7150/jca.29285

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