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State‐of‐the‐art CRISPR /Cas9 Technology for Genome Editing in Trypanosomatids

18 Jun 2019

Abstract excerpt

CRISPR/Cas9 technology has revolutionized biology. This prokaryotic defense system against foreign DNA has been repurposed for genome editing in a broad range of cell tissues and organisms. Trypanosomatids are flagellated protozoa belonging to the order Kinetoplastida. Some of its most representative members cause important human diseases affecting millions of people worldwide, such as Chagas disease, sleeping...

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PMID: 31211904
DOI: 10.1111/jeu.12747

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