Article
Dietary iron variably modulates assembly of the intestinal microbiota in colitis-resistant and colitis-susceptible mice.
Gut microbes - 1 Jan 2020
Ellermann Melissa, Gharaibeh Raad Z, Maharshak Nitsan, Peréz-Chanona Ernesto, Jobin Christian, Carroll Ian M, Arthur Janelle C, Plevy Scott E, Fodor Anthony A, Brouwer Cory R, Sartor R Balfour
Abstract excerpt
Iron deficiency, a common comorbidity of gastrointestinal inflammatory disorders such as inflammatory bowel diseases (IBD), is often treated with oral iron supplementation. However, the safety of oral iron supplementation remains controversial because of its association with exacerbated disease activity in a subset of IBD patients. Because iron modulates bacterial growth and function, one possible mechanism by...
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