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Article

FBXW7 Mutations Promote Cell Proliferation, Migration, and Invasion in Cervical Cancer

30 May 2019

Abstract excerpt

Aim: Cervical cancer is the most common gynecological cancer. Recent studies have revealed that the F-box and WD repeat domain containing 7 ( FBXW7 ) gene, which encodes a subunit of Skp1-Cul1-F-box protein (SCF) ubiquitin ligase, is frequently mutated in cervical squamous cell carcinomas. In this study, we investigated whether Chinese cervical cancer cells also harbor these mutations. Methods: Using PCR and...

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Identifiers

PMID: 31161818
DOI: 10.1089/gtmb.2018.0278

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