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Article

Evidence of Trained Immunity in a Fish: Conserved Features in Carp Macrophages

24 May 2019

Abstract excerpt

Abstract Trained immunity is a form of innate immune memory best described in mice and humans. Clear evidence of the evolutionary conservation of trained immunity in teleost fish is lacking. Given the evolutionary position of teleosts as early vertebrates with a fully developed immune system, we hypothesize that teleost myeloid cells show features of trained immunity common to those observed in mammalian...

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PMID: 31127029
DOI: 10.4049/jimmunol.1900137

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