Neuropathological and genomic characterization of glioblastoma‐induced rat model: How similar is it to humans for targeted therapy?

Abstract excerpt

Glioblastoma multiforme (GBM) is a unique aggressive tumor and mostly develops in the brain, while rarely spreading out of the central nervous system. It is associated with a high mortality rate; despite tremendous efforts having been made for effective therapy, tumor recurrence occurs with high prevalence. To elucidate the mechanisms that lead to new drug discovery, animal models of tumor progression is one of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Glioma Diagnosis and Treatment
• Share to Microtubule and mitosis dynamics
• Share to Protein Degradation and Inhibitors