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Article

Salmonella enterica persister cells form unstable small colony variants after in vitro exposure to ciprofloxacin.

Scientific reports - 10 May 2019

Drescher Samara Paula Mattiello, Gallo Stephanie Wagner, Ferreira Pedro Maria Abreu, Ferreira Carlos Alexandre Sanchez, Oliveira Sílvia Dias de

Abstract excerpt

Persistence phenotype and small colony variants (SCVs) can be part of a bacterial bet-hedging strategy for survival under environmental stresses, such as antimicrobial exposure. These phenotypes are of particular concern in persistent and relapsing infections, since cells resume to normal growth after cessation of the stressful condition. In this context, we found persisters and unstable SCVs as phenotypic...

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Topics

Anti-Bacterial Agents
Biofilms
Ciprofloxacin
Microbial Sensitivity Tests
Microscopy, Electron, Scanning

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Phenotype

Salmonella enterica

Source

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Identifiers

PMID: 31076596
DOI: 10.1038/s41598-019-43631-7
PMCID: PMC6510897

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