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Article

Identification of ESM1 overexpressed in head and neck squamous cell carcinoma

2 May 2019

Abstract excerpt

BACKGROUND: Endocan, also known as endothelial cell specific molecule-1 (ESM1), is a 50 kDa soluble proteoglycan which is frequently overexpressed in many cancer types. Whether it is dysregulated in head and neck squamous cell carcinoma (HNSCC) has not been investigated. METHODS: We analyzed the expression of ESM1 using bioinformatics analysis based on data from The Cancer Genome Atlas (TCGA), and then validated...

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PMID: 31073279
DOI: 10.1186/s12935-019-0833-y

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