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Gestational exposure to low‐dose zearalenone disrupting offspring spermatogenesis might be through epigenetic modifications

6 May 2019

Abstract excerpt

Zearalenone (ZEA), a F-2 mycotoxin produced by Fusarium, has been found to be an endocrine disruptor through oestrogen receptor signalling pathway to impair spermatogenesis. The disruption on reproductive systems by ZEA exposure might be transgenerational. In our previous report, we have found that low dose (lower than no-observed effect level, NOEL) of ZEA impaired mouse spermatogenesis and decreased mouse semen...

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PMID: 31058416
DOI: 10.1111/bcpt.13243

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